Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase (EC184.108.40.206, SHIP1, SHIP2, SHIP, p150Ship) is an enzyme with system name 1-phosphatidyl-1D-myo-inositol-3,4,5-trisphosphate 5-phosphohydrolase. This enzyme catalyses the following chemical reaction
This enzyme hydroylses 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2.
"First" is a song by American indie rock band Cold War Kids. The song was written by the band and produced by Lars Stalfors and Dann Gallucci. It was the second single off their fifth album Hold My Home (2014) and was released on February 17, 2015. The song received a positive reception from music critics.
"First" peaked at number 1 on the Billboard Alternative Songs chart, becoming the band's highest charting single. A music video was made for the single and was released on January 12, 2015.
"First" received positive reviews from music critics. Philip Cosores of Paste called it a "clap-along anthem" and said that together with "All This Could Be Yours" and "Hot Coals", is "the strongest run the band has put together in its career." Heather Phares of AllMusic remarked the song being a highlight of the album due to its "anthemic power."
The music video was uploaded on the band's VEVO page on January 12, 2015.
The song appeared on the Billboard Alternative Songs chart at number 40 and peaked at number 1, their first song to top that chart. It has stayed on the chart for twenty-eight weeks (as of the October 24, 2015 chart date), making it their longest charting single to date.